I have been fighting to get Skype to work so that I could make calls. Getting PulseAudio to work with Skype has been a challenge. (“Back to Alsa”, “Sound in Jaunty”).
I recently found out that the latest version supports PulseAudio natively! You can download it from here. Currently, they are at version 2.1.0.47.
Previously, I had downloaded from the Medibuntu repository, which you can see here. But, they only offer version 2.0.0.72.
One thing I noticed is that they recommend version 0.9.15 or greater. You can check to see what version you have with this command:
pulseaudio –version
So, here is a screenshot of the audio setup screen for this new version of Skype. Notice that PulseAudio is an option now.
It takes some fiddling about, but it works.